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Here is what is known so far, and answers that are needed to provide more context on the attack.
How many people were killed?
In the first hours after the blast, a Gaza civil defence chief said 300 people were killed, while health ministry sources put the figure at 500.

Wounded Palestinians wait for treatment in al-Shifa Hospital in Gaza City, central Gaza Strip, after arriving from al-Ahli Arab Hospital following an explosion there. Source: AAP, AP / Abed Khaled
An Israeli spokesperson said the casualty numbers were inflated.
What happened before the strike?
Israel previously told Palestinians in the north of Gaza, including in Gaza City, to move south for their own safety. Israel’s military specifically told residents of the Zeitoun district of Gaza City to move south on Tuesday in a message issued on social media platform X.
The Kuwaiti specialist hospital in Rafah city, in the south of Gaza, said on Monday it had received two Israeli warnings to evacuate but its director said its staff would not leave.
What details do we have about the strike?
Dr Fadel Naim, head of orthopaedic surgery at the al-Ahli Arab Hospital, said he had finished one surgery and was about to start another when he heard a huge explosion. Another doctor at the hospital, Ibrahim Al-Naqa, spoke to Reuters about the scenes at the hospital in the attack’s aftermath. He said the blast took place at about 6.30pm local time on Tuesday.
Live footage from the Al-Jazeera media network aired at 18:59 local time showed a bright light rising in the skies above Gaza. It flashes twice before drastically changing direction, and it then explodes.
What was the damage?
Footage and images obtained by Reuters from inside the hospital showed about two dozen destroyed vehicles on its grounds.

They were surrounded by damaged buildings with windows blown out. Blood stains were on the walls and the ground.
What do we know about the hospital?
Founded in 1882 and run by the Anglican church, al-Ahli Arab Hospital is described on its website as “a haven of peace in the middle of one of the world’s most troubled places”. The hospital offered 80 beds with services such as a free program to detect breast cancer, a centre for elderly women, and a mobile clinic offering free services to surrounding towns.
It is located in the Zeitoun neighbourhood of Gaza City, in the northern region of the Gaza Strip.
How many people were in the hospital?
Naim said about 1,000 people were in al-Ahli Arab Hospital on Tuesday morning and more were rushed there later in the day after he said the Israeli army had warned residents in the Zeitoun neighbourhood to evacuate their homes.

A Palestinian girl carries blankets as she walks past the site of a deadly explosion at al-Ahli Arab Hospital in Gaza. Source: AAP / Abed Khaled/AP
Naqa said more than 3,000 people had sought refuge at the hospital at the time of the strike.
What does US intelligence say about the blast?
The strike has inflamed Arab governments and groups in the region. Protesters took to the streets in several Arab countries denouncing what they said was an Israeli strike on the hospital.
In Lebanon, Iran-based Hezbollah, which fought a war with Israel in 2006, denounced what it called Israel’s deadly attack and called for protests on Wednesday. The Beirut government declared a national day of mourning.
What have Gaza officials said about the blast?
The health ministry spokesman, Ashraf Al-Qudra, said early on Wednesday that hundreds were killed and that rescue workers were still removing bodies from the rubble.
What has Israel said?
Israeli military spokesperson Rear Admiral Daniel Hagari told reporters rockets fired by the Palestinian Islamic Jihad militant group passed by the hospital at the time of the strike, which he said hit the facility’s parking lot.
This has not been verified.
What about other groups?
What information is missing about the blast?
BBC Verify said it spoke to three experts who said the explosion is not consistent with what you would expect from a typical Israeli air strike with a large munition, but also spoke to three experts who gave other responses.
Verified figures on the number of people killed have not been published yet.
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